Thermo Fisher Scientific CTLA4 Monoclonal Antibody (OTI2E9)
인간 CTLA4에 반응하는 마우스 단클론 항체로 Flow Cytometry에 적합. 무보존제, 동결건조 형태로 제공되며 친화 크로마토그래피로 정제됨. 재구성 및 결합 실험에 최적화된 고순도 연구용 시약.
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Applications
- Flow Cytometry (Flow): Tested dilution 1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E9 |
| Immunogen | Full length human recombinant protein of human CTLA4 (NP_005205) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor primarily expressed on CD4+ T cells. It binds CD80 and CD86 on B cells and dendritic cells with higher affinity than CD28. Unlike CD28, which enhances T cell activation, CTLA4 inhibits T cell function. Intracellular CTLA4 is also found in regulatory T cells and is important for their activity.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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