Thermo Fisher Scientific CTLA4 Monoclonal Antibody (OTI3D2)
인간 CTLA4 단백질을 인식하는 마우스 단클론 항체로, Flow Cytometry에 1:400 희석으로 사용 가능. 무보존제, 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도. 연구용으로 T세포 억제 기전 연구에 적합.
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Applications
- Flow Cytometry (Flow): Tested Dilution 1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D2 |
| Immunogen | Full length human recombinant protein of human CTLA4 (NP_005205) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor mainly expressed on CD4+ T cells. It binds CD80 and CD86 on B cells and dendritic cells with higher affinity than CD28. Unlike CD28, which enhances T cell activation, CTLA4 inhibits T cell function. Intracellular CTLA4 is also found in regulatory T cells and contributes to their suppressive activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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