
Thermo Fisher Scientific CTLA4 Monoclonal Antibody (OTI7D3)
CTLA4 단백질을 인식하는 Mouse IgG1 단일클론 항체. 인간 시료에 반응하며 Flow Cytometry에 적합. 동결건조 형태로 제공되며 PBS와 트레할로스 버퍼에 보관. 연구용으로 세포 면역억제 기전 연구에 활용 가능.
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Applications
- Flow Cytometry (Flow): 1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7D3 |
| Immunogen | Full length human recombinant protein of human CTLA4 (NP_005205) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor primarily expressed on CD4+ T cells. It binds CD80 and CD86 with higher affinity than CD28, resulting in inhibition of T cell activation. Intracellular CTLA4 is also present in regulatory T cells and plays a role in their suppressive function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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