Thermo Fisher Scientific Heparin Cofactor II Polyclonal Antibody
Human Serpin D1/Heparin Cofactor II에 특이적인 염소 다클론 항체로, Western blot, IP, Neutralization에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS + 5% trehalose buffer에 동결건조 형태로 제공. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunoprecipitation (IP) | 25 µg/mL |
| Neutralization (Neu) | 6.6 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Sf 21-derived recombinant human Serpin D1/Heparin Cofactor II (Gly20–Ser499) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609697 |
Product Specific Information
- In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant mouse Serpin D1 is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin.
The gene contains five exons and four introns.
This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily.
Mutations in this gene are associated with heparin cofactor II deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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