
Thermo Fisher Scientific Heparin Cofactor II Polyclonal Antibody
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Applications
Tested Dilution
Publications
Western Blot (WB)
0.1 µg/mL
Immunoprecipitation (IP)
25 µg/mL
Neutralization (Neu)
6.6 µg/mL
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Sf 21-derived recombinant human Serpin D1/Heparin Cofactor II Gly20-Ser499 if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
Heparin Cofactor II,
uniProtId:
P05546-1,
ncbiNodeId:
9606,
antigenRange:
20-499,
antigenLength:
499,
antigenImageFileName:
PA5-47466_Heparin_Cofactor_II_P05546-1_Goat.svg,
antigenImageFileNamePDP:
PA5-47466_Heparin_Cofactor_II_P05546-1_Goat_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609697
Product Specific Information
In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant mouse Serpin D1 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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