Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Monoclonal Antibody (KRT14/4132)
사람 KRT14 단백질을 인식하는 단클론 항체로, 편평세포 표지자로 사용됩니다. 파라핀 절편 및 PFA 고정 조직의 면역조직화학(IHC)에 적합하며, 단백질 A/G로 정제된 액상 형태입니다. 4°C에서 보관하며, 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2c, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KRT14/4132 |
| Immunogen | Recombinant fragment (around aa351–472) of human KRT14 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cytokeratins (CK) are intermediate filaments of epithelial cells found in both keratinizing tissues (e.g., skin) and non-keratinizing cells (e.g., mesothelial cells). At least 20 different CKs have been identified. Most CKs belong to either type I (acidic) or type II (basic) classes.
Keratin 14 (KRT14), a type I low molecular weight keratin, pairs with keratin 5 and serves as a marker distinguishing stratified epithelial cells from simple epithelial cells. It is particularly useful in identifying squamous cell carcinomas and is considered a prognostic marker in breast carcinomas. At least one acidic and one basic keratin are expressed in all epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
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