Thermo Fisher Scientific Cytokeratin 13 (Non-Keratinized Squamous Epithelial Marker) Monoclonal Antibody (rKRT13/9623)
비각질화 편평상피세포의 마커로 사용되는 Cytokeratin 13 단클론 항체. IHC(P)에서 1–2 µg/mL 농도로 사용 가능. Human 시료 반응성, Mouse IgG2b 동종형. Protein A/G 정제, PBS + 0.05% BSA 보존. HeLa, A431 세포 양성 대조군 권장.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rKRT13/9623 |
| Immunogen | Esophageal keratins of rabbit origin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: HeLa or A431 cells, Skin, or Squamous cell carcinoma
Target Information
Cytokeratins are a subfamily of intermediate filament proteins exhibiting significant biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. These range in molecular weight between approximately 40 kDa and 68 kDa, with isoelectric points between 4.9 and 7.8.
Individual human cytokeratins are numbered 1 to 20. Expression patterns vary by epithelial type and differentiation stage, aiding in distinguishing epithelial malignancies.
Cytokeratin antibodies are valuable tools in tumor differential diagnosis using immunohistochemistry, and also useful in cytopathology and flow cytometric assays.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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