Thermo Fisher Scientific MASP1 Polyclonal Antibody
Human MASP1 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체입니다. Western blot 및 Immunoprecipitation에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 동결건조 형태로 제공되며, 연구용으로만 사용됩니다.
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Thermo Fisher Scientific MASP1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1 µg/mL |
| Immunoprecipitation (IP) | 25 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Complement Factor MASP3 Ile450–Val721 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608683 |
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
MBL is a key component in immune response, directly triggering neutralization of invading microorganisms by an antibody-independent mechanism. Mutations of human MBL are associated with immunodeficiency due to reduced complement fixation ability.
In humans, three MBL-associated serine proteases—MASP-1, MASP-2, and MASP-3—and a truncated form of MASP-2 (sMAP or MAp19) complex with MBL to activate the lectin pathway of the complement system.
MASP-3 is an alternatively spliced product from the MASP-1 gene. The heavy/A chains are identical between MASP-1 and MASP-3, while the light/B chains differ completely. Activated MASPs subsequently cleave and activate downstream components of the complement pathway.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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