
Thermo Fisher Scientific TIAM 1 Polyclonal Antibody
TIAM1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 IHC에 적합. 인간, 마우스, 랫트 반응성. PBS 기반 무보존제 제형이며, 장기 보관 시 -20°C에서 안정적. 세포 부착 및 이동 관련 연구에 활용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of human T-lymphoma invasion and metastasis-inducing protein 1 (TIAM1) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TIAM1.
Target Information
TIAM1 modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities.
Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them.
Activates RAC1, CDC42, and to a lesser extent RHOA.
Required for normal cell adhesion and cell migration.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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