Thermo Fisher Scientific Phospho-MKK7 (Ser271, Thr275) Recombinant Rabbit Monoclonal Antibody (MKK7S271T275-R4F9), PE
PE 형광 표지된 재조합 rabbit monoclonal antibody로, 인간 MKK7의 Ser271 및 Thr275 인산화 부위를 특이적으로 인식. Flow cytometry에 적합하며, 고순도 Protein A/G 정제. 안정적 PBS/BSA buffer에 보존되어 연구용으로 사용 가능.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MKK7S271T275-R4F9 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser271 and Thr275 of human MKK7 |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896941 |
Additional Formats
- Unconjugated: MA5-37005
- APC: MA5-37008
- FITC: MA5-37007
- Custom conjugation available upon request
Target Information
The protein encoded by this gene is a dual specificity protein kinase belonging to the MAP kinase family. It specifically activates MAPK8/JNK1 and MAPK9/JNK2, and is itself phosphorylated and activated by MAP kinase kinases such as MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK. This kinase mediates cellular responses to proinflammatory cytokines and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified, with one transcript variant well defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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