Thermo Fisher Scientific Phospho-MKK7 (Ser271, Thr275) Recombinant Rabbit Monoclonal Antibody (MKK7S271T275-R4F9)
Phospho-MKK7 (Ser271, Thr275) 인산화 부위를 인식하는 재조합 토끼 단클론 항체입니다. Western blot 및 유세포분석에 적합하며, 높은 특이성과 재현성을 제공합니다. HEK293 세포에서 발현된 recombinant IgG 항체로, 단백질 신호전달 연구에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: 1–1,000 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MKK7S271T275-R4F9 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser271/Thr275 of human phospho MKK7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896940 |
Additional Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened to select the best candidates.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to the rabbit immune repertoire
Target Information
The encoded protein is a dual specificity protein kinase of the MAP kinase family. It activates MAPK8/JNK1 and MAPK9/JNK2 and is itself phosphorylated by MAP kinase kinases such as MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK.
This kinase mediates cellular responses to proinflammatory cytokines and environmental stresses. Multiple alternatively spliced transcript variants exist, but only one has been defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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