Thermo Fisher Scientific Phospho-MKK7 (Ser271, Thr275) Recombinant Rabbit Monoclonal Antibody (MKK7S271T275-R4F9), FITC
FITC 결합된 재조합 토끼 단일클론 항체로 인간 MKK7의 Ser271 및 Thr275 인산화 부위를 인식합니다. Flow Cytometry에 적합하며, 고순도 Protein A/G 정제 및 안정적 PBS-BSA buffer로 제공됩니다. 연구용으로 세포 신호전달 분석에 활용됩니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MKK7S271T275-R4F9 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser271 and Thr275 of human MKK7 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896942 |
Additional Formats
- Unconjugated (MA5-37005)
- APC (MA5-37008)
- PE (MA5-37006)
- Custom conjugation available upon request
Target Information
The protein encoded by this gene is a dual specificity protein kinase belonging to the MAP kinase family. It specifically activates MAPK8/JNK1 and MAPK9/JNK2 and is phosphorylated and activated by upstream kinases including MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK. This kinase mediates cellular responses to proinflammatory cytokines and environmental stresses. Multiple alternatively spliced variants exist, but only one has been well-defined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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