Thermo Fisher Scientific Phospho-Chk1 (Ser317) Recombinant Rabbit Monoclonal Antibody (Chk1S317-F10), PE
PE 형광 표지된 Phospho-Chk1 (Ser317) 항체로 인간 및 마우스 샘플에 반응. Flow Cytometry에 최적화된 5 µL/10^6 cells 사용. HEK293 발현 시스템 기반 재조합 단클론 항체. DNA 손상 체크포인트 연구용으로 적합.
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Thermo Fisher Scientific Phospho-Chk1 (Ser317) Recombinant Rabbit Monoclonal Antibody (Chk1S317-F10), PE
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | Chk1S317-F10 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser317 of human phospho Chk1 |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896937 |
Additional Formats
Target Information
CHEK1 (CHK1) is a serine/threonine protein kinase involved in preventing replication when DNA integrity is compromised. CHK1 is a key mediator in the DNA damage-induced checkpoint network and functions to ensure genomic integrity upon genotoxic stress. Inhibition of CHK1 can lead to mitotic catastrophe and apoptosis in p53-deficient cancer cells, making Chk1 an attractive therapeutic target for cancer treatment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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