Thermo Fisher Scientific IL17RB Polyclonal Antibody
IL17RB 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간 IL17RB 재조합 단백질로 면역화되었으며, 비결합형 액상 형태로 제공됩니다. 순도 95% 이상이며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:4,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein of human IL17RB |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719990 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
A number of cytokines belonging to the interleukin (IL)-17 family have been identified, including IL-17B, IL-17C, and IL-17E. IL-17 is a potent proinflammatory cytokine involved in diseases such as rheumatoid arthritis, multiple sclerosis, and tumor growth. IL-17B, C, and E can induce proinflammatory responses but do not bind to the IL-17 receptor, suggesting the existence of additional IL-17R-related receptors. Receptors for IL-17B and IL-17E have been identified as EV127 (mouse) and IL-17Rh1 (human), respectively. IL-17E activates the NF-κB pathway and induces IL-8 production. IL-17Rh1 mRNA is highly expressed in kidney and liver, and moderately in small intestine, colon, and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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