Thermo Fisher Scientific TGF-beta 2 Polyclonal Antibody
TGF-beta 2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), IP 실험에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 세포 내 위치는 막 및 세포질이며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
| Immunoprecipitation (IP) | 2–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full-length recombinant protein of human TGF-beta 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Placenta
- Cellular location: Membrane and cytoplasmic.
Target Information
Transforming Growth Factor (TGF) betas mediate many cell-to-cell interactions that occur during embryonic development. Three TGF betas (TGF-beta 1, TGF-beta 2, and TGF-beta 3) have been identified in mammals. Each is synthesized as a precursor protein, cleaved to yield a 112 amino acid polypeptide associated with the latent portion of the molecule.
TGF-beta polypeptides are multifunctional, influencing cell proliferation, differentiation, and various cellular functions. Both transformed and nonneoplastic tissues release transforming growth factors, and most mammalian cells possess specific TGF receptors.
TGF-beta exhibits dual roles in cellular proliferation: stimulating mesenchymal cells while inhibiting epithelial or neuroectodermal cells. Although TGF-beta 1, TGF-beta 2, and TGF-beta 1.2 share similar biological activity, they differ in receptor binding affinity. TGF-beta 2 is produced by many cell types and is abundant in porcine platelets and mammalian bone. Latent TGF-beta 2 is the main isoform found in body fluids such as amniotic fluid, breast milk, and ocular humors.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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