
Thermo Fisher Scientific MEKK4 Polyclonal Antibody
MEKK4 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot, IHC, ELISA 등 다양한 응용에 적합. 고순도 Affinity Chromatography 정제, 안정적 PBS/glycerol buffer 구성. 연구용으로만 사용.
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Thermo Fisher Scientific MEKK4 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human MAP3K4 (NP_005913.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.35 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914077 |
Product Specific Information
- Positive test controls: K-562, Rat brain
- Immunogen sequence:
MREAAAALVP PPAFAVTPAA AMEEPPPPPP PPPPPPEPET ESEPECCLAA RQEGTLGDSA CKSPESDLED FSDETNTENL YGTSPPSTPR QMKRMSTKHQ
Target Information
This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo, affecting its interaction with TBP. It contains:
- Histone fold motif at the amino terminus
- TBP-binding domain
- Glutamine- and alanine-rich region
Binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which altered DNA conformation and higher order complex formation inhibit assembly of the preinitiation complex, controlling RNA polymerase II transcription rate.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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