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Thermo Fisher Scientific MEKK4 Polyclonal Antibody
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Thermo Fisher Scientific MEKK4 Polyclonal Antibody

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MEKK4 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot, IHC, ELISA 등 다양한 응용에 적합. 고순도 Affinity Chromatography 정제, 안정적 PBS/glycerol buffer 구성. 연구용으로만 사용.

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마지막 업데이트 2025. 08. 04. 오전 04:52
Thermo Fisher Scientific PA5120505 MEKK4 Polyclonal Antibody 100 ul pk판매 단위 pk ·
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710,700원VAT 포함 781,770원

Thermo Fisher Scientific · Thermo Fisher Scientific MEKK4 Polyclonal Antibody

Thermo Fisher Scientific MEKK4 Polyclonal Antibody

Applications and Tested Dilutions

Application Tested Dilution
Western Blot (WB) 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P)) 1:100–1:200
ELISA 1 µg/mL

Product Specifications

Specification Description
Species Reactivity Human, Rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic peptide corresponding to amino acids 1–100 of human MAP3K4 (NP_005913.2)
Conjugate Unconjugated
Form Liquid
Concentration 1.35 mg/mL
Purification Affinity Chromatography
Storage Buffer PBS, pH 7.3, with 50% glycerol
Contains 0.01% thimerosal
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Wet ice
RRID AB_2914077

Product Specific Information

  • Positive test controls: K-562, Rat brain
  • Immunogen sequence:
    MREAAAALVP PPAFAVTPAA AMEEPPPPPP PPPPPPEPET ESEPECCLAA RQEGTLGDSA CKSPESDLED FSDETNTENL YGTSPPSTPR QMKRMSTKHQ

Target Information

This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo, affecting its interaction with TBP. It contains:

  • Histone fold motif at the amino terminus
  • TBP-binding domain
  • Glutamine- and alanine-rich region

Binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which altered DNA conformation and higher order complex formation inhibit assembly of the preinitiation complex, controlling RNA polymerase II transcription rate.

Safety Information

WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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