Thermo Fisher Scientific ATP Citrate Lyase Recombinant Rabbit Monoclonal Antibody (ST51-07)
ATP Citrate Lyase 단백질을 검출하기 위한 재조합 토끼 단클론 항체로, WB, IHC, ICC/IF, Flow, IP 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. 고순도 Protein A 정제, 1 mg/mL 농도. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:200 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ST51-07 |
| Immunogen | Synthetic peptide within C-terminal human ATP citrate lyase (UniProt ID: P53396-1, NCBI Node ID: 9606, Antigen Range: 1101, Antigen Length: 1101) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2911573 |
Product Specific Information
- Positive Control: A549 cell lysate, CRC cell lysate, HeLa cell lysate, Wild-type A549 whole cell lysates, HeLa, A549, CRC, human thyroid tissue, human breast carcinoma tissue, mouse thyroid tissue, mouse kidney tissue
- Subcellular Location: Cytoplasm, nucleoplasm
Target Information
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- MA5-42432_ATP_Citrate_Lyase_P53396-1_Rabbit.svg
- MA5-42432_ATP_Citrate_Lyase_P53396-1_Rabbit_PDP.jpeg
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