Thermo Fisher Scientific LRP12 Polyclonal Antibody
Thermo Fisher Scientific의 LRP12 Polyclonal Antibody는 인간 및 생쥐 시료에서 LRP12 단백질 검출용으로 적합합니다. 항원 친화 크로마토그래피로 정제되어 순도 95% 이상이며, Western blot에 최적화된 고품질 항체입니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human LRP12 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2719352 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Members of the LDL receptor gene family, including LDLR (low density lipoprotein receptor), LRP1 (low density lipoprotein related protein), Megalin (GP330), VLDLR (very low density lipoprotein receptor), and ApoER2 are characterized by clusters of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats, and an O-linked sugar domain.
LRP12 (also designated ST7) is a member of this family, thought to be involved in the internalization of lipophilic molecules and/or signal transduction. LRP12 interacts with RACK1, MADHIP, and Integrin beta-1-binding protein 3. It is widely expressed in heart, skeletal muscle, brain, lung, placenta, and pancreas. Overexpression of LRP12 may be associated with oral tumors, suggesting its potential role as an oncogene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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