Thermo Fisher Scientific Amylin Peptide Polyclonal Antibody
Thermo Fisher Scientific의 Amylin Peptide Polyclonal Antibody는 인간 Amylin 단백질을 인식하는 토끼 다클론 항체입니다. IHC(P) 및 ELISA에 적합하며, 항원 친화 정제 방식으로 높은 특이성과 재현성을 제공합니다. 연구용으로 당뇨병 관련 연구에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
| ELISA | 0.01–0.1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from N-terminus of human Amylin peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Pancreas tissue
- Cellular location: Cytoplasmic
Target Information
Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering from type II diabetes mellitus or harboring an insulinoma. Although the association of amylin with type II diabetes has long been recognized, its direct causative role remains under investigation. Studies suggest that amylin, similar to beta-amyloid (Abeta) involved in Alzheimer’s disease, can induce apoptotic cell death in certain cultured cells, potentially contributing to the pathogenesis of type II diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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