Thermo Fisher Scientific Ubiquitin Polyclonal Antibody
Rabbit polyclonal antibody recognizing ubiquitin protein. Validated for IHC (paraffin) with broad species reactivity. Supplied as liquid, 0.5 mg/mL, purified by antigen affinity chromatography. Recommended storage at 4°C short term or -20°C long term. ...
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 2–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | All, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of ubiquitin protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Human brain from Alzheimer’s disease
- Cellular location: Nuclear, cytoplasmic, and cell membrane
Target Information
Ubiquitin is a highly conserved protein that plays a key role in targeting cellular proteins for degradation by the 26S proteasome. It is synthesized as a precursor protein, either as polyubiquitin chains or as a single ubiquitin fused to another protein. The gene encodes a fusion protein consisting of ubiquitin at the N-terminus and ribosomal protein S27a at the C-terminus. Post-translational processing generates free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a, a component of the 40S ribosomal subunit, contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene exist in the genome. Similar fusion proteins include ribosomal proteins L40 and S30, which are synthesized with ubiquitin or ubiquitin-like proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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