Thermo Fisher Scientific CTLA4 Monoclonal Antibody (UMAB249), UltraMAB
인간 CTLA4 단백질을 인식하는 UMAB249 클론의 마우스 단일클론 항체. 파라핀 조직 IHC에 적합하며, 무보존제·동결건조 형태로 제공. 재구성 후 1 mg/mL 농도로 사용 가능하며, 연구용으로 CTLA4 관련 면역반응 분석에 활용.
- 카탈로그번호
- UM800141CF
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- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB249 |
| Immunogen | Full length human recombinant protein of human CTLA4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor mainly expressed on CD4+ T cells. It binds CD80 and CD86 on B cells and dendritic cells with higher affinity than CD28. Unlike CD28, CTLA4 inhibits T cell activation and function. Intracellular CTLA4 is also found in regulatory T cells and plays a role in their function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: UM800141CF_CTLA-4_CD152_P16410-1_House_mouse.svg)
(이미지: UM800141CF_CTLA-4_CD152_P16410-1_House_mouse_PDP.jpeg)
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