Thermo Fisher Scientific CTLA4 Monoclonal Antibody (UMAB249), UltraMAB
인간 CTLA4 단백질을 인식하는 Mouse IgG1 단일클론 항체로, IHC(P)에서 1:200 희석으로 사용 가능. 비결합형 액상 형태이며 PBS/BSA/glycerol 완충액에 보관. T세포 억제 관련 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB249 |
| Immunogen | Full length human recombinant protein of human CTLA4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed mainly on CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity. Unlike CD28, which enhances T cell activation, CTLA4 inhibits T cell function. Intracellular CTLA4 is also found in regulatory T cells and may be critical to their function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- UM800141_CTLA-4_CD152_P16410-1_House_mouse.svg
- UM800141_CTLA-4_CD152_P16410-1_House_mouse_PDP.jpeg
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