Thermo Fisher Scientific TSC22D1 Recombinant Rabbit Monoclonal Antibody (110)

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:20–1:100

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to prevent contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences are cloned from immunoreactive rabbits, and individual clones are screened for optimal performance.

Advantages:

• High specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broad immunoreactivity due to rabbit immune repertoire

This antibody specifically recognizes human TSC22D1.

Target Information

TSC22 domain family protein (TSC22) is a transcription factor belonging to the early response gene family. It acts as a transcriptional repressor on the C-type natriuretic peptide (CNP) promoter and is part of the TSC-22/Dip/Bun family. TSC22 is localized in the cytoplasm or nucleus and regulates cell growth, differentiation, and apoptosis. It modulates the transcriptional activity of Smad3 and Smad4 and is expressed ubiquitously in both fetal and adult tissues, including aortic endothelial cells. Expression is induced by cytokines such as TGFB. TSC22 proteins are potential therapeutic targets in leukemia and prostate cancer.

For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.