Thermo Fisher Scientific GPIP137 Polyclonal Antibody
Western blot, IHC, ICC 등 다양한 응용에 적합한 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트 반응성. CAPRIN1 유래 합성 펩타이드 항원 사용. 고순도 Affinity chromatography 정제, -20°C 보관.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CAPRIN1 (Accession Q14444), corresponding to amino acid residues S436–A486 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899577 |
Product Specific Information
Antibody detects endogenous levels of total CAPRIN1.
Target Information
GPIP137 regulates the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation/migration in multiple cell types.
It binds directly and selectively to MYC and CCND2 RNAs.
In neuronal cells, GPIP137 binds to several mRNAs associated with RNA granules including BDNF, CAMK2A, CREB1, MAP2, NTRK2, GRIN1, and KPNB1 mRNAs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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