Thermo Fisher Scientific GRAP Polyclonal Antibody
GRAP 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P)에서 검증됨. Human과 Mouse에 반응하며, 항원 친화 크로마토그래피로 정제됨. 1 mg/mL 농도의 액상 제품으로, 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 시약.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–202 of Human GRAP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547878 |
Product Specific Information
- Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7, mouse brain
- Predicted reactivity: Mouse (94%), Rat (93%), Rhesus Monkey (98%), Bovine (92%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein containing an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, facilitating formation of a stable complex with the BCR-ABL oncoprotein. It also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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