Thermo Fisher Scientific Calpain 9 Polyclonal Antibody
Human Calpain 9 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 1–191 of Human Calpain 9 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547879 |
Product Specific Information
- Recommended positive controls: 293T, A431, Jurkat, Raji
- Predicted reactivity: Mouse (89%), Rat (90%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Calpains are a family of calcium-dependent cysteine proteases composed of an invariant small subunit and variable large subunits. The large subunit contains a cysteine protease domain, and both subunits have calcium-binding domains. Calpains are implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress.
Calpain 9 is predominantly expressed in the stomach and small intestine, suggesting specialized functions in the digestive tract and possible association with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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