Thermo Fisher Scientific CD98 Chimeric Recombinant Rabbit Monoclonal Antibody (RL388)
CD98 단백질을 인식하는 재조합 토끼 단클론 항체로, 마우스 시료에 반응합니다. Western blot, ICC/IF, Flow cytometry, Immunoprecipitation, T-cell activation 등 다양한 응용에 적합합니다. 고순도 Protein A 정제, 액상 형태, 1 mg/mL 농도로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.05 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
| T-Cell Activation (TCA) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RL388 |
| Immunogen | This antibody was raised by immunising rats with an IL-2-producing subline of the mouse T lymphoma EL4. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074653 |
Product Specific Information
This antibody recognizes murine CD98, a heterodimeric cell surface glycoprotein.
Target Information
CD98 (4F2) is a type II transmembrane glycoprotein that serves as the heavy chain of heterodimeric amino acid transporters (HATs). CD98 forms disulfide bonds with various light chains, enabling cell surface expression and basolateral localization of the transporter complex in polarized epithelial cells. It also interacts with β1 integrins, enhancing their ligand affinity. Beyond amino acid transport, CD98 is involved in cell fusion, activation, and regulation of cellular differentiation, growth, and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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