Thermo Fisher Scientific TYRP1 Chimeric Recombinant Human Monoclonal Antibody (TA99)
TYRP1 표적 인간 단일클론 항체로 멜라닌 생합성 연구에 적합. Western blot, IHC, ICC/IF, Flow, ELISA, IP 등 다양한 응용 가능. HEK293 발현, Protein A 정제, 1 mg/mL 농도. 멜라닌 생성 관련 단백질 분석용 연구 시약.
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Frozen) (IHC (F)): Assay-dependent
- Immunocytochemistry (ICC/IF): Assay-dependent
- Flow Cytometry (Flow): Assay-dependent
- ELISA (ELISA): Assay-dependent
- Immunoprecipitation (IP): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | TA99 |
| Immunogen | 70–75 kDa pigmentation-associated glycoprotein in human melanoma cell lines |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
Binds Tyrosinase-related protein-1 (TRP-1), a 70–75 kDa enzyme located in melanocytes. TRP-1 stabilizes tyrosinase, the enzyme responsible for the first step in melanin production, and determines the shape of melanosomes, the structures in melanocytes where melanin is produced.
Target Information
This gene encodes a melanosomal enzyme belonging to the tyrosinase family, playing an important role in the melanin biosynthetic pathway. Defects in this gene cause rufous oculocutaneous albinism and oculocutaneous albinism type III.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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