Thermo Fisher Scientific Phospho-HSP27 (Ser82) Monoclonal Antibody (GT357)
Phospho-HSP27 (Ser82)을 인식하는 GT357 단클론 항체로, 인간·마우스·랫트 시료에서 사용 가능. Western blot 및 면역세포염색에 적합. 단백질 A로 정제된 액상 항체이며, 장기 보관 시 -20°C에서 안정적.
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Thermo Fisher Scientific Phospho-HSP27 (Ser82) Monoclonal Antibody (GT357)
Applications and Tested Dilutions
- Western Blot (WB): 1:1,000–1:10,000
- Immunocytochemistry (ICC/IF): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT357 |
| Immunogen | Carrier-protein conjugated synthetic peptide corresponding to residues around human HSP27 (phospho Ser82). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2866541 |
Target Information
Cells respond to environmental stress by increasing expression of heat shock proteins (HSPs).
HSPB1 (heat shock protein beta-1, also known as HSP27) acts as a molecular chaperone, maintaining denatured proteins in a folding-competent state.
It contributes to stress resistance and actin organization, and regulates processes such as phosphorylation and axonal transport of neurofilament proteins.
Mutations in HSPB1 may result in Charcot-Marie-Tooth disease 2F and distal hereditary motor neuronopathy type 2B.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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