Thermo Fisher Scientific EED Monoclonal Antibody (GT885)
EED 단백질을 인식하는 마우스 모노클로날 항체로 Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. Protein G 정제, PBS 용액 형태. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT885 |
| Immunogen | Recombinant protein encompassing a sequence within the center region of Human EED (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.54 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2866544 |
Target Information
The EED protein (WAIT-1 or WD protein associated with integrin cytoplasmic tails-1), also called embryonic ectoderm development, is a member of the superfamily of WD-40 repeat proteins and the widely conserved polycomb group (PcG) family of proteins. PcG proteins form multimeric complexes that modify histones, leading to stable and heritable transcriptional repression. EED shuttles between the nucleus and plasma membrane and interacts with the cytoplasmic tail of the integrin Beta-7 subunit. It has been reported to exert antiviral activity at the late stage of HIV-1 replication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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