Thermo Fisher Scientific DRG1 Polyclonal Antibody
DRG1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며, 인간과 생쥐 시료에서 반응. 항원 친화 크로마토그래피로 정제된 고품질 항체로 연구용으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to residues near the C-terminal of human developmentally regulated GTP binding protein 1 (DRG1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635851 |
Product Specific Information
The antibody detects endogenous levels of total DRG1 protein.
Target Information
Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP (PubMed:29915238, PubMed:23711155).
Appears to have intrinsic GTPase activity stimulated by ZC3H15/DFRP1 binding, likely by increasing the affinity for potassium ions (PubMed:23711155).
When hydroxylated at C-3 of Lys-22 by JMJD7, may bind to RNA and play a role in translation (PubMed:19819225, PubMed:29915238).
Binds to microtubules and promotes microtubule polymerization and stability required for mitotic spindle assembly during prophase to anaphase transition.
GTPase activity is not necessary for these microtubule-related functions (PubMed:28855639). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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