Thermo Fisher Scientific CD144 (VE-cadherin) Monoclonal Antibody (55-7H1)
인간 CD144(VE-cadherin)을 인식하는 마우스 단클론 항체로, 세포 간 접착 연구에 적합합니다. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용에 사용 가능하며, Protein A로 정제된 액상 항체입니다. 4°C 보관, 동결 금지.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-Dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-Dependent |
| Immunocytochemistry (ICC/IF) | Assay-Dependent |
| Flow Cytometry (Flow) | 1–4 µg/mL |
| Immunoprecipitation (IP) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 55-7H1 |
| Immunogen | Human endothelial cells (target: VE-cadherin/CD144, UniProt ID: P33151-1, antigen range: 1–784) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745500 |
Additional Formats
Product Specific Information
This antibody recognizes a calcium-independent extracellular epitope on CD144 (VE-cadherin, cadherin 5), an adhesion molecule expressed on endothelial cells.
Target Information
VE-cadherin is a member of the cadherin superfamily located in a six-cadherin cluster on chromosome 16. It is a calcium-dependent cell-cell adhesion glycoprotein with five extracellular cadherin repeats, a transmembrane region, and a conserved cytoplasmic tail. VE-cadherin plays a crucial role in endothelial cell biology by regulating intercellular junction cohesion and organization. An alternative splice variant has been described, though the full-length sequence has not been determined.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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