Thermo Fisher Scientific Major Vault Protein (MVP) Monoclonal Antibody (1032)
인간 Major Vault Protein(MVP)을 인식하는 mouse monoclonal antibody입니다. IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합하며, Protein A/G로 정제된 고순도 제품입니다. 약물 내성 연구 및 세포 내 단백질 수송 관련 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1032 |
| Immunogen | Proteins precipitated from human breast cancer MCF-7 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes the major vault protein, a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, possibly via a transport process. It is widely distributed in normal tissues and overexpressed in multidrug-resistant cancer cells. Overexpression of this protein is a potentially useful marker of clinical drug resistance.
This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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