Thermo Fisher Scientific Major Vault Protein (MVP) Monoclonal Antibody (1014)
Human Major Vault Protein(MVP)에 특이적인 Mouse Monoclonal Antibody(클론 1014). Western blot, ICC/IF, Flow Cytometry 등 다양한 응용 가능. Protein A/G로 정제된 고순도 항체로 PBS buffer에 보존. 약물 저항성 연구 및 세포 내 단백질 수송 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1–2 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 1–2 µg/10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1014 |
| Immunogen | Proteins precipitated from human breast cancer MCF-7 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes the major vault protein (MVP), a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. MVP mediates drug resistance, possibly via a transport process. It is widely distributed in normal tissues and overexpressed in multidrug-resistant cancer cells. Overexpression of this protein is a potentially useful marker of clinical drug resistance.
This gene produces two transcripts using alternative exon 2 sequences; both share the same open reading frame.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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