Thermo Fisher Scientific HOXD12 Polyclonal Antibody
HOXD12 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 사용 가능. Human 및 Mouse 시료에 반응하며, PBS와 50% glycerol 용액에 보관. 발달 및 세포 분화 관련 연구에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HOXD12 (Accession P35452), corresponding to amino acid residues A68–S118. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818222 |
Product Specific Information
Antibody detects endogenous levels of total HOXD12.
Target Information
The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis.
Hox proteins are involved in controlling axial patterning, leukemias, and hereditary malformations.
HoxD12 (homeobox D12), also known as HOX4H, is a 275 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. It functions as a sequence-specific transcription factor important for the correct positioning of developing limb buds on the anterior-posterior axis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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