Thermo Fisher Scientific ZNF174 Polyclonal Antibody
ZNF174 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. Human 및 Rat 시료에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 완충액에 보관되며 -20°C에서 안정적입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ZNF174 (Accession Q15697), corresponding to amino acid residues P189–S239 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818219 |
Product Specific Information
Antibody detects endogenous levels of total ZNF174.
Target Information
ZNF174 (also known as ZSCAN8 or AW-1) is a transcriptional repressor belonging to the Krueppel C2H2-type zinc-finger protein family. It is expressed in multiple tissues including small intestine, prostate, colon, spleen, pancreas, skeletal muscle, brain, heart, kidney, and thymus, with predominant expression in adult ovary and testis.
ZNF174 represses promoter activities of PDGF-B and TGF beta1. It localizes to the nucleus and contains three C2H2-type zinc fingers at the C-terminus and one SCAN domain near the N-terminus. SCAN domains are conserved regions of approximately 84 residues that regulate noncovalent complex formation and selective oligomerization among SCAN-containing proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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