Thermo Fisher Scientific ZHX2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 488-837 of human ZHX2 (NP_055758.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ZHX2,uniProtId:Q9Y6X8-1,ncbiNodeId:9606,antigenRange:488-837,antigenLength:837,antigenImageFileName:PA5-120626_ZHX2_Q9Y6X8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120626_ZHX2_Q9Y6X8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914198

Product Specific Information

Positive test controls include: U-251MG, 293T, Raji, LO2, Mouse brain.

Immunogen sequence: SDHRYRCQRG IVHITSESLA KDQLAIAASR HGRTYHAYPD FAPQKFKEKT QGQVKILEDS FLKSSFPTQA ELDRLRVETK LSRREIDSWF SERRKLRDSM EQAVLDSMGS GKKGQDVGAP NGALSRLDQL SGAQLTSSLP SPSPAIAKSQ EQVHLLRSTF ARTQWPTPQE YDQLAAKTGL VRTEIVRWFK ENRCLLKTGT VKWMEQYQHQ PMADDHGYDA VARKATKPMA ESPKNGGDVV PQYYKDPKKL CEEDLEKLVT RVKVGSEPAK DCLPAKPSEA TSDRSEGSSR DGQGSDENEE SSVVDYVEVT VGEEDAISDR SDSWSQAAAE GVSELAESDS DCVPAEAGQA

Target Information

Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys(2)-His(2)-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.