Thermo Fisher Scientific GLIPR1 Polyclonal Antibody
GLIPR1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(P) 분석에 적합. Human 및 Mouse에 반응하며, 항원 친화 크로마토그래피로 정제됨. p53 조절 관련 종양 억제 단백질 연구에 활용 가능.
- 카탈로그번호
- PA538023
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | 18 amino acid peptide near the center of human GLIPR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2554627 |
Product Specific Information
- Recommended positive control: mouse small intestine tissue lysate
- At least two isoforms of GLIPR1 are known to exist; this antibody detects both isoforms.
- Not expected to cross-react with other GLIPR or GLIPR-like proteins.
Target Information
The glioma pathogenesis-related protein 1 (GLIPR1) shares similarity with the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family.
GLIPR1 functions as a tumor suppressor regulated by p53. Increased expression is associated with myelomocytic differentiation in macrophages, while decreased expression due to gene methylation is linked to prostate cancer.
GLIPR1 is part of a p53 target gene cluster that includes GLIPR1L1 and GLIPR1L2, which are highly homologous proteins with distinct expression patterns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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