Thermo Fisher Scientific PGC1 alpha Polyclonal Antibody
PGC1 alpha 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC, Flow Cytometry 등에 사용 가능. 인간, 마우스, 랫트 시료에 반응하며, 에너지 대사 관련 유전자 연구에 적합. 냉장 또는 -20°C 장기보관 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 8 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL | View publications |
| Immunocytochemistry (ICC/IF) | – | View 1 publication |
| Flow Cytometry (Flow) | – | View publications |
Product Specifications
| Item | Description |
|---|---|
| Published species | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | 17 amino acid peptide near the amino terminus of human PPARGC1A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C. |
| Shipping conditions | Wet ice |
| RRID | AB_2554626 |
Product Specific Information
- Recommended positive control: human heart tissue lysate
- Detects all three known isoforms of PPARGC1A
Target Information
PGC1 alpha is a transcriptional coactivator that regulates genes involved in energy metabolism. It interacts with PPARγ and multiple transcription factors, including CREB and NRFs, linking physiological stimuli to mitochondrial biogenesis. PGC1 alpha also influences muscle fiber type determination, blood pressure control, cholesterol homeostasis, and obesity development.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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