Thermo Fisher Scientific ATMIN Polyclonal Antibody
ATMIN 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 ICC/IF에 적합. 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 제품으로 안정적인 1 mg/mL 농도 유지. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | 19 amino acid peptide near the amino terminus of human ATMIN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2554629 |
Product Specific Information
- Recommended positive control: 293 cell lysate
- At least three isoforms of ATMIN are known to exist.
Target Information
The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51.
ATMIN is also involved in embryonic development; absence of ATMIN leads to late-embryonic lethality in mice with multiple organ development defects.
It activates transcription of DYNLL1, a light chain of the dynein motor complex and regulator of protein dimerization.
DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a dynamic feedback loop for DYNLL1 expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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