Thermo Fisher Scientific LAG3 Monoclonal Antibody (OTI10E7), TrueMAB
LAG3 단백질을 인식하는 Mouse IgG2a 단일클론 항체로 Western blot 및 유세포분석에 적합. 인간 시료에 반응하며, 동결건조 형태로 제공. PBS 버퍼에 8% 트레할로스 함유, 보존제 무첨가. 재구성 후 1 mg/mL 농도로 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific LAG3 Monoclonal Antibody (OTI10E7), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:2,000 | - |
| Flow Cytometry (Flow) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10E7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 66–332 of human LAG3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | –20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, an additional desalting step is recommended (Zeba Spin Desalting Columns, 7 K MWCO, 0.5 mL, Product #89882).
Target Information
LAG-3 (Lymphocyte Activation Gene 3) is a 70 kDa surface glycoprotein belonging to the immunoglobulin superfamily, homologous to CD4. It binds MHC class II with higher affinity than CD4 and is involved in the negative regulation of T cell activation and homeostatic proliferation.
LAG-3 is expressed on activated T cells (including regulatory T cells) and NK cells. CD8⁺ T cells typically express higher levels than CD4⁺ T cells. Coexpression of LAG-3 and CD49b identifies human and mouse Type 1 regulatory T cells (Tr1 cells).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.