Thermo Fisher Scientific n-Myc Polyclonal Antibody
Rabbit polyclonal antibody recognizing human N-Myc protein. Validated for Western blot and flow cytometry. High specificity without cross-reactivity to other Myc family members. Supplied as liquid form, affinity purified, for research use only.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Flow Cytometry (Flow) | - | 1 publication |
| Miscellaneous PubMed (Misc) | - | 2 publications |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues surrounding lysine 351 of human N-Myc |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 31.1 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 50% glycerol, 100 µg/mL BSA |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10988360 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other Myc family members.
Target Information
N-Myc protein is a member of the MYC family of transcription factor proteins with a basic helix-loop-helix (bHLH) domain. N-Myc is similarly regulated and functionally complementary to C-Myc in various cellular growth and differentiation processes.
The MYCN gene is considered the hallmark of neuroblastoma; amplification and overexpression of the MYCN proto-oncogene occur in approximately 20% of neuroblastomas and are associated with advanced-stage disease, rapid tumor progression, and poor prognosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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