Thermo Fisher Scientific alpha N-Catenin Polyclonal Antibody
Human, Mouse, Rat 반응성을 가진 Rabbit Polyclonal 항체로, alpha N-Catenin을 검출. WB, ICC/IF, Flow, IP 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제되었으며, 보존제 없이 -20°C에서 저장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:800 |
| Flow Cytometry (Flow) | 1:50 |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the carboxy-terminus of human α-N-catenin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11008462 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other alpha-catenin family members.
Target Information
The catenins (alpha, beta, and gamma) are cytoplasmic proteins found in varying abundance in many developing and adult tissues. Catenins bind directly or indirectly to the conserved cytoplasmic tail domain of the cell adhesion cadherins. The association of catenins to cadherins produces a complex linked to the actin filament network. These complexes play a key role in mediating cell adhesion, transmitting cell-cell contact signals, and contributing to cell differentiation. Alpha-Catenin (CAP102, 102 kDa), originally described as an E-cadherin associated protein, also associates with other cadherin family members such as N-cadherin and P-cadherin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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