Thermo Fisher Scientific USP6NL Polyclonal Antibody
Human USP6NL 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:50~1:100 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(pH 7.4)와 50% 글리세롤 용액에 보존. RAB5A 및 RAB43 관련 수용체 트래픽 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human USP6NL (aa 451–500) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635614 |
Product Specific Information
This antibody detects endogenous levels of total USP6NL protein.
Target Information
USP6NL acts as a GTPase-activating protein for RAB5A and RAB43, and is involved in receptor trafficking.
In complex with EPS8, it inhibits internalization of EGFR.
It participates in retrograde transport from the endocytic pathway to the Golgi apparatus and is involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network.
Required for maintaining the structural integrity of the Golgi complex.
[Source: UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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