Thermo Fisher Scientific THOC5 Polyclonal Antibody
THOC5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(Paraffin)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. THOC5의 내인성 발현 검출에 적합. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human THOC5 (aa 561–610) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635613 |
Product Specific Information
This antibody detects endogenous levels of total THOC5 protein.
Target Information
THOC5 is a component of the THO subcomplex within the TREX complex, which associates specifically with spliced mRNA. The TREX complex is recruited to mRNA in a splicing- and cap-dependent manner and plays a critical role in mRNA export. THOC5, in conjunction with THOC4, participates in NXF1-NXT1 mediated nuclear export of HSP70 mRNA and may be involved in granulocyte and adipocyte differentiation. The TREX complex is also essential for the export of Kaposi’s sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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