Thermo Fisher Scientific Cytokeratin, Acidic (Type I or LMW) Recombinant Rabbit Monoclonal Antibody (KRTL, 1577R)
Cytokeratin, Acidic (Type I or LMW) 단백질을 인식하는 재조합 토끼 단클론 항체. IHC(P)에서 1–2 µg/mL로 사용 가능. 사람 및 개 시료에 반응하며, HEK293 발현 시스템에서 생산. Protein A/G 정제, 4°C 보관.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | KRTL, 1577R |
| Immunogen | Recombinant human KRT77 protein fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
This antibody is expected to show broad species reactivity.
For immunohistochemistry (PFA fixed): incubate antibody for 30 minutes at room temperature.
For formalin-fixed tissues, heat tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, then cool at room temperature for 20 minutes.
Target Information
Cytokeratin pan is part of a subfamily of intermediate filament proteins characterized by biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides.
Cytokeratins range in molecular weight between 40–68 kDa and have isoelectric points between 4.9–7.8.
Different epithelia express specific cytokeratin profiles related to tissue type, maturation, and differentiation.
Cytokeratin subtype patterns are useful in distinguishing epithelial malignancies, aiding tumor diagnosis via immunohistochemistry, cytopathology, and flow cytometry.
Keratins serve as valuable markers in cancer research and tumor diagnostics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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