Thermo Fisher Scientific H3K4me1 Polyclonal Antibody
H3K4me1 단일메틸화 히스톤 H3를 인식하는 Rabbit Polyclonal 항체. Western blot, ICC/IF, ELISA, ChIP 등 다양한 응용 가능. Human, Mouse, Xenopus, Zebrafish 반응성. 연구용으로만 사용.
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Thermo Fisher Scientific H3K4me1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ELISA | 1:100 |
| ChIP assay (ChIP) | - |
| Peptide Array (Array) | 1:1,000 |
| Dot blot (DB) | 1:50,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Xenopus, Zebrafish |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Raised against histone H3 containing the monomethylated lysine 4 (H3K4me1), using a KLH-conjugated synthetic peptide. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | <0.1% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
| RRID | AB_2533854 |
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Post-translationally, histones are modified in various ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several types of post-translational modification that influence cellular processes, including methylation or acetylation of lysine and arginine residues and phosphorylation of serine or threonine.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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