Thermo Fisher Scientific PDCD1 Monoclonal Antibody (OTI9G6), TrueMAB
PDCD1 단백질을 인식하는 마우스 단클론 항체로, Flow Cytometry에 적합합니다. 인간 및 마우스 시료 반응성이 있으며, Lyophilized 형태로 제공됩니다. PBS 버퍼에 보관하며, 재구성 후 1 mg/mL 농도로 사용 가능합니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9G6 |
| Immunogen | Full length human recombinant protein of human PDCD1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform another round of desalting (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Cell-mediated immune responses are initiated by T lymphocytes stimulated by peptides bound to MHC molecules on antigen-presenting cells (APC). Activated T cells express inhibitory receptors such as PD-1 (PDCD-1), which bind ligands PDL-1 and PDL-2 to suppress immune activation in the absence of danger signals. PD1-deficient mice show hyperactivated immune systems and autoimmune symptoms. PD-1 may migrate at higher molecular weight than predicted in SDS-PAGE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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