Thermo Fisher Scientific PDCD1 Monoclonal Antibody (OTI27G3), TrueMAB
PDCD1 단백질을 인식하는 마우스 단클론 항체로, 인간 및 마우스 시료에 반응합니다. Flow Cytometry에 적합하며, 동결건조 형태로 제공됩니다. PBS 버퍼에 8% 트레할로스를 포함하고 보존제가 없습니다. 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow): 1:50 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI27G3 |
| Immunogen | Full-length human recombinant protein of human PDCD1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Cell-mediated immune responses are initiated by T lymphocytes stimulated by peptides bound to MHC molecules on antigen-presenting cells (APC).
Activated T cells express inhibitory receptors such as PD-1 (also known as PDCD-1), which bind ligands PDL-1 and PDL-2 to inhibit immune activation in the absence of danger signals.
PD-1 knockout mice show hyperactive immune responses and autoimmune diseases.
Despite its predicted molecular weight, PD-1 often migrates at a higher molecular weight in SDS-PAGE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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