Thermo Fisher Scientific MARK4 Monoclonal Antibody (OTI9B7), TrueMAB
MARK4 단백질을 인식하는 Mouse monoclonal antibody로, WB와 IHC(P)에서 검증됨. Human, Mouse, Rat 반응성. Lyophilized 형태, PBS buffer(8% trehalose) 보존. 세포주기 및 미세소관 조절 관련 연구에 적합.
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Applications
- Western Blot (WB): Assay-dependent
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9B7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 390–467 of human MARK4 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
MARK4 is a serine/threonine kinase involved in microtubule organization in neuronal cells. It localizes to the centrosome during mitosis and may play a role in cell cycle control. Expression of MARK4 has been linked to cancer and Alzheimer’s disease. Pseudogenes are found on both arms of chromosome 3, and multiple isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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