Thermo Fisher Scientific NMDAR2C Polyclonal Antibody
Rabbit polyclonal antibody targeting NMDAR2C subunit of rat NMDA receptor. Suitable for Western blot at 1:1,000 dilution. Plays key role in CNS studies related to memory and neuronal development. For research use only.
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- 485400
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- Publications: [References available upon request]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein from the N-terminus of the NR2C-subunit of rat NMDA receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2533848 |
Target Information
The NMDA Receptor (NMDAR) plays an essential role in memory and neuronal development. It is implicated in several central nervous system disorders such as Alzheimer’s disease, epilepsy, and ischemic neuronal cell death. The NMDA receptor is also a principal molecular target for alcohol in the CNS and is potentiated by protein phosphorylation. The NR1 protein can form NMDA-activated channels when expressed in Xenopus oocytes, but the currents are smaller than those observed in situ. Channels with more physiological characteristics are produced when the NR1 subunit combines with one or more of the NMDAR2 (NR2 A-D) subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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